Firefox has a very old bug related to rendering an HTML string to the DOM without escaping it, that one has bit me a few times. Nothing a tiny inline script can't fix, but its frustrating to have such a basic feature fail.
Debugging is also pretty painful, or I at least haven't found a good dev setup for it.
That said, I'm happy to reach for XSLT when it makes sense. Its pretty amazing what can be done with such an old tech, for the core use case of props and templates to HTML you really don't need react.