Or maybe "optimizing for the most personal wealth over anything else" and "optimizing for the longest healthy lifespan over anything else" are two different goals, pursued by different people.

As a result, extreme results in one or the other are not usually attained by people who do not have extreme prioritization of just one.

It is totally possible that a rare talented unicorn pursuing (and succeeding at) both goals simultaneously is needed for us to achieve radical life extension.