alt Hacker Newsthis is such an interesting problem. Imagine expanding the input size to 3.2Gbp, the size of human genome. I wonder if previously unimaginable interactions would occur. Also interesting how everything revolves around U-nets and transformers these days.
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eleveriven • today at 7:08 AM
Even just modeling 3D genome organization or ultra-long-range enhancers more realistically could open up new insights
teaearlgraycold • yesterday at 6:27 PM
> Also interesting how everything revolves around U-nets and transformers these days.
To a man with a hammer…
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You would not need much more than 2 megabases. The genome is not one contiguous sequence. It is organized (physically segregated) into chromosomes and topologically associated domains. IIRC 2 megabases is like the 3 sd threshold for interactions between cis regulatory elements / variants and their effector genes.