PSA:

0. Always use a) SECDED hardware ECC and b) checksums on network links and I/O everywhere.

1. When unable to 1.a), add (72,64) 8-bits Hamming code per 64-bits (or) N>2 redundancy copies on physically-separate silicon for critical data and code. This is a significant performance hit, but safety is more important in some uses. (Don't neglect the integrity and reliability of code storage, loading, and execution paths either.)

2. Consider using Space Shuttle high-availability, high-reliability "voting" of N identically-designed behavior, possibly different manufacturer system control elements.