Apparently it's about software, not hardware - Qualcomm recommends running Android under a virtual machine (which lacks nested virtualization support).
Is this for real? Do you have any more info on this? It seems crazy to me given how popular their chips are and how many problems I’d imagine this creates
IIRC Qualcomm smartphone SoCs have always run some kind of hypervisor, I believe it's to allow partitioning of the CPU cores with the modem/DSP.
They used to (mid-late 2000s) use an L4 derivative ("REX"?), with the more recent chips (including the 'X' series for PCs) using their homegrown "Gunyah" hypervisor (https://github.com/quic/gunyah-hypervisor)