Yes with a but:

NixOS simultaneously smooths the path to using absolute paths while putting some (admittedly minor) speed-bumps in the way when avoiding them. If you package something up that uses relative paths it will probably break for someone else relatively quickly.

What that means is that you end up with a system in which absolute paths are used almost everywhere.

This is why the killer feature of NixOS isn't that you can configure things from a central place; RedHat had a tool to do that at least 25 years ago; it's that since most of /etc/ is read-only, you must configure everything from a central place, which has two important effects:

1. The tool for configuring things in a central place can be much simplified since it doesn't have to worry about people changing things out from under it

2. Any time someone runs into something that is painful with the tool for configuring things in a central place, they have to improve the tool (or abandon NixOS).