Alpha Centauri is only 4.2 light years away. 0.25c is definitely enough to reach it. You could even do a round trip in only your adult years.
A trip there to do… what?
There likely won’t be any planet better than the very low bar of Mars for human habitation, in fact maybe even worse due to binary perturbations.
Yeah, if you take the highly unlikely and already lethat 0.25c achievability as a given.