alt Hacker NewsThat’s really neat.
I’m ashamed that I have this wish that I were overweight and had an excuse to try a GLP1 just to see how it would affect my impulse control with non-food habits.
I guess there’s not much stopping me from buying some unregulated drugs from the internet and self-experimenting, but I haven’t heard experiences from people deliberately using them for anything but weight.
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Depending on your appetite for risk, there's always the gray market. It's also a lot cheaper depending on what your insurance covers. I think I picked up a year's supply of semaglutide for under $200. I've been on some form of GLP for the last 2 years and for me there have been several tangible benefits related to ADHD.
https://gray.guide is a good starting point.
It would probably be interesting, but if you are not overweight, the appetite suppression will likely make this not a very healthy or very fun experiment. I started at 5mg in October, and even on that smaller dose I had to force myself to eat even just ~800kcal a day - especially in the early weeks. When you have a lot of weight to lose, that's a pretty welcome effect. When you are already at a healthy weight, not so much. That caloric intake would put most adults into a pretty deep caloric deficit.
I'd suspect if the effects on non-weight indications check out in studies, we might see drugs that could specifically target those effects without also slowing down your digestive tract. Addictions like nicotine and alcoholism and their consequences cost health insurance companies (and us as a society) billions of Euros/Dollars each year, so there'd be a strong incentive to pursue this.
If it helps, I don't think that there is anything to be ashamed of to want to try new things even if you recognize it is inadvisable. If there were no physical consequences, I'd like to try all sorts of medicines to see what effect they would have on me.
As a user of Mounjaro, obtained from a doctor, I find the experience very interesting. It has all sorts of weird side effects that I don't expect. As a bioinformatician in training it's great fun to speculate about the causes, pathways, signals, and whatnot that might be involved as this drug perturbs so much stuff in my system.
It's not pleasurable per se, but it is interesting. I have changed my food habits significantly without actually trying. I think I was too impatient to eat to cook if that makes sense. Weirdly, foods taste better to me which I did not expect. I also have found myself really enjoying my hobbies more. This has resulted in a lot of 3d printer filament purchases, so my impulse control may not have been helped much.
As far as experimenting on yourself, it will likely require the cumulative effect of weeks or months to notice changes in non-food habits if such changes occur at all.
There's probably some online doctor that will prescribe this thing to you for several hundred dollars/euros or whatever. You may suffer greatly for your curiosity, though. There are instances of very unpleasant side effects, some of which I experience personally.