This looks like a very comfortable, pleasant way of civilization suicide.

Not interacting with any other human means you're the last human in your genetic line. A widespread adherence to this idea means humanity dwindling and dying out voluntarily. (This has been reproduced in mice: [1])

Not having humans as primary actors likely means that their interests become more and more neglected by the system of machines that replaces them, and they, weaker by the day, are powerless to counter that. Hence the idea of increased comfort and well-being, and the ability to do science, is going to become more and more doubtful as humans would lose agency.

[1]: https://www.smithsonianmag.com/smart-news/this-old-experimen...