I guess it depends on what "large file" and "regular size SD card" mean to you.

The best selling SD card on B&H is 128 GB. Let's consider that "regular size".

Fujifilm's GFX100 II is a popular medium-format mirrorless camera. Its sensor is 102MP. So each 14-bit RAW image is about 170 MB.

102M pixels x 14 bits = 1.428B bits = ~178M bytes = ~170 MB

So a 128 GB SD card can hold ~771 images that are 170 MB. That's a lot more images than a standard roll of film.