By minimizing apps on device, blocking all traffic to Apple 17.x, using Charles Proxy (and NetGuard on Android) to allowlist IP/port for the remaining apps at the router level, and then manually inspecting all other network activity from the device. Also the disappearance of said traffic after hard-reset.
Sometimes there were anomalies in app logs (iOS Settings - Analytics) or sysdiagnose logs. Sadly iOS 26 started deleting logs that have been used in the past to look for IOCs.
Are you sure whatever you have configured in the MDM profile or one of these apps like Charles Proxy is not the source of the traffic?
Are you using a simple config profile on iOS to redirect DNS and if so how are you generating it ? Full MDM or what are you adding to the profile ?
How did you determine that a connection was malicious? Modern apps are noisy with all of the telemetry and ad traffic, and that includes a fair amount of background activity. If all you’re seeing are connections to AWS, GCP, etc. it’s highly unlikely that it’s a compromise.
Similarly, when you talk about it going away after a reset that seems more like normal app activity stopping until you restart the app.