On windows and linux, yes, without any added anything holding the shift (or windows or control or alt) key on one keyboard will modify the behavior of any key with any other keyboard (I have a vague memory of getting 3 keyboards and hitting ctl-alt-del across the three keyboards, on windows, and it behaving "normally").

You need some added tools to make it work with macos, as someone else pointed out

These days I just use a single keyboard (the IBM M4-1 keyboard) and get up frequently.