There’s not much difference, really. I stupidly didn’t bother looking at prior art when I started reverse engineering and the ghidra-cli was born (along with several others like ilspy-cli and debugger-cli)

That said, it should be easier to use as a human to follow along with the agent and Claude Code seems to have an easier time with discovery rather than stuffing all the tool definitions into the context.

I also did this approach (scripts + home-brew cli)...because I didn't know Ghidra MCP servers existed when I got started.

So I don't have a clear idea of what the comparison would be but it worked pretty well for me!