There are simulators for this, and of course there's data from places that have actually done it.

In Dublin we have a bit of a mixture of newish bus routes which largely have a sensible number of stops, and ancient routes (the oldest evolved out of tram routes laid out in the 1870s), which tend to have a stupidly high number of stops, because once you put one in it's very contentious to remove it. The super-regular stop routes are _so slow_.