alt Hacker NewsRight. Opioids are an absolute terror to one's digestive system. When I had chronic pain I would rather have just accepted the pain than deal with the gut consequences.
LDN is an interesting one since it just stimulates your body to generate its own endorphins.
I found the first week on LDN to be challenging due to "horror flick" vivid dreams.
LDN reduces "central amplification" of neuropathic pain, so it is a good fit for my disease profile.