You're right that you can't test comments, but you can test the code they describe. That's what reproducibility bundles do in scientific computing ;; the prose says "we filtered variants with MAF < 0.01", and the bundle includes the exact shell command, environment, and checksums so anyone can verify the prose matches reality. The prose becomes a testable claim rather than a decorative comment. That said, I agree the failure mode of literate programming is prose that drifts from code. The question is whether agents reduce that drift enough to change the calculus.