The Osprey has a reputation, for sure, but it's mid-pack. They called the F-104 the widow maker for a reason, for example. And the F-16 has a fairly high accident rate, too, slightly higher than the Osprey. Though I think the F-16's history is a bit more lopsided, they made some changes after early production airframes proved pretty accident prone.
In Turkey, F-104 was called “flying coffin”.