In the book The Cuckoo's egg, Cliff Stoll talks to I think Luiz Alvares. I don't have the book handy here, but Alvarez basically told him to nit get distracted by grants, bosses, ... Here is interesting science to do, so go for it. Just run faster than the rest of the world.

In a way, it was a sidetrack of the book, but for me the attitude speaking from that text was interesting and inspiring. When I could pull it off, it tended to work.