Is this where I can complain about command+q? All day every day I use command+tab/tilde/w/a/s, and smack in the middle of that is command q. It's like if automobile manufacturers decided to put a third pedal between the accelerator and the brake that immediately shuts off your car in the middle of the highway. And you can't disable it, instead you can map it to such helpful things like... invert colors.
Not only can disable it, but with the right tools like Karabiner elements you can turn it into something useful - double tap cmd+Q to quit: no accidental activations, but retains muscle memory
Not perfect, but this exists https://commandqapp.com
In System Settings > Keyboard Shortcuts > App Shortcuts, add the shortcut: app Safari, name "Quit Safari", command-option-Q. This will leave command-Q doing nothing, yet still allow you to quit. Repeat for other apps.
For me it’s Ctrl + C / V. I will frequently hit Ctrl + C when I want to paste, and some software helpfully copies a blank line to the clipboard if nothing is selected, thus erasing whatever I copied.