Is cross compilation out of the question?
Near as I know, Fedora prefers native compilation for the builds.
Your question made me look up Arm's history in Fedora and came up on this 2012 LWN thread[1]. There's some discussion against cross-compilation already back then.
It's usually an enormous pain to set up. QEMU is probably the best option.
I'd guess that the issue is running the `%install` and `%check` stages of the .spec file. The Python library rpy (to pull a random example from Marcin's PRs) runs rpy's pytest test suite and had to be modified to avoid running vector tests on RISC-V.
Obviously a solvable problem to split build and test but perhaps the time savings aren't worth the complexity.
https://src.fedoraproject.org/rpms/rpy/pull-request/4#reques...