This seems to be a recent anti-science meme to dismiss studies that use mouse models. I'm sure there is an interesting line of discussion about the strengths and limits of those models, but that's probably a complex, nuanced thread to pull, not something you blow off with a hand-waving internet comment.
I wish I could filter the word mice or mouse out of hn comments because as you say every single one are low effort gotcha's that I will never get my time back from.
It is like these armchair scientists don't understand that the actual scientists know the limits of the model system better than they do.
It's not anti-science, it's anti-science-journalism-hype.
Science depends on accurately reporting facts, being clear about the limits of your findings, and seeking explanations that survive scrutiny. Science journalism has other priorities that are often in conflict with those of science.
I bet it started with people trying to 1-up other commenters via the usual “achtually…” and then proceeding with the “in mice” notice.
To some degree the other posts are just pointing out the misleading "assumed protagonist" of the title (which doesn't mention mice) but I was surprised to see that the majority of posts boiled down to "eek! mice!"