alt Hacker NewsI only have marginal knowledge about neuroscience, but one of my neuroscience professors in class would tell us
"You can cure anything in mice."
I don't know the mechanism why, but you can find tons of papers with incredibly strong results for curing of mitigating dementia, cognitive decline, addiction, etc in mice, but these almost never seen to work on people.
Replies
mustaphah • today at 12:25 AM
I guess it's because most major disorders and diseases have so many pathways at play that figuring out which one's actually causing the problem at the individual level is just too tricky.
The other thing concerns how potent the effect is to be therapeutic. In many cases, the effect is just marginal to be meaningful.
They're human specific ailments. We create a fake version of them in mice, then we fix the fake version. The basic problem with these issues is we don't understand the root cause. So we can replicate the symptoms in a mouse model then fix the symptoms, but that doesn't work in humans because the root cause is still there.