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idiotsecantyesterday at 12:38 AM2 repliesview on HN

The blood brain barrier is a deny by default firewall. If there is no transporter configured for a particular molecule, it doesn't get through. There is no transporter for serotonin


Replies

sooheonyesterday at 1:42 PM

Your nervous system extends over your entire body, the brain doesn't live in a firewalled jar.

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bitexploderyesterday at 12:52 AM

See: vagal neurons and vagus nerve. Serotonin from gut directly impacts those. Your brain still directly interprets that signal from the vagus nerve and uses that to up and down regulate mood and arousal. Impact is still significant