This might not be the first to break, but it will eventually, and if corrected NOW will make things much smoother:
Your documentation of processes and procedures is NOT adequate.
'everyone used to know about are getting lost' - oh good thing your documentation makes this clear, because it is obviously their fault.
'New hires take forever to ramp up' - oh good thing you have complete ramp up plan and documentation, because it is obviously their fault.
'building on different assumptions' - oh good, your old assumptions are clearly documented, because it is obviously their fault.
So their is your self focus, please do good, and document well.
So, documentation is the solution? But do people have time to document everything?
Are you saying there's too much undocumented tribal knowledge? If so, I agree
Docs help, but they don't save you from a team that treats Slack as the source of truth. At 50 people the bigger failure is ownership: nobody knows which page is current, nobody gets time to fix stale docs after the process changes, and after a few rounds of that the wiki becomes a museum piece new hires learn to ignore.