Largely, DNS integrity has been addressed by making it harder to spoof dns responses without visibility.

Resolvers have put in the effort to use most of the range of source ports and all of the range of request ids, as well as mixed caps, so predicting queries is difficult and blind spoofing requires an unreasonable number of packets.

Additionally, commercial DNS services tend to be well connected anycast. This means most queries can be served with a very low round trip time; reducing the spoofing window. Additionally, there's less opportunity to observe requests as they traverse fewer networks and less distance.

Generally, traffic has moved to certificate authenticated protocols. CAs are required to verify domain control from multiple locations, so an attacker asserting domain control would need to do so for the victim as well as multiple other locations in order to get a certificate issued.

Further; if we assume you plan to assert domain control by taking over or MITMing the IP of a DNS server, it seems likely you could do the same for the IP of an application server. DNSSEC doesn't help very much in that case. (DNSSEC with DANE could help in that case, but to a first approximation, nothing supports that, and there doesn't appear to be any movement towards it)

It seems pretty clear to me that the industry, and particularly the slice of the industry that operates large, important sites and staffs big security teams, doesn't believe this is a meaningful problem at all.

I agree with them.

It will change as soon as one of them gets meaningfully DNS hijacked.