alt Hacker Newshttps://www.home-assistant.io/installation/generic-x86-64/
you mean an image like this?
This is what I've been running on my generic x86-64 system for a couple of years now, 0 issues. Even migrated to a newer system recently because I wanted something that was slightly faster for ESPHome compilations.
"self-installing" being the key point. Those instructions require you to use some other piece of software to write the image onto your boot disk. In my case I used an Ubuntu livecd to download and write the image to the machine. It's obviously not a showstopper but it is slightly annoying.