Sounds like you might benefit from something like the UHK[1].
It's got tenting, which approaches that natural tilt to your hands, and there are several mouse add-ons to choose from, I'm sure one of them will suit your needs.
Yeah, something like that is awfully appealing. I don't have as much trouble with typing as with trackpadding for whatever happy combination of reasons, the biggest being that I taught myself to type after playing piano for many years first, and so completely ignored "proper" home-row typing in favor of piano-like "move your hand around and wiggle your fingers" typing. I'm still one of the faster typists I know, so doing it "wrong" hasn't held me back at all.
But. If my hands start to hurt while typing, I'm definitely trying something like that as my first keyboard experiment.
Yeah, something like that is awfully appealing. I don't have as much trouble with typing as with trackpadding for whatever happy combination of reasons, the biggest being that I taught myself to type after playing piano for many years first, and so completely ignored "proper" home-row typing in favor of piano-like "move your hand around and wiggle your fingers" typing. I'm still one of the faster typists I know, so doing it "wrong" hasn't held me back at all.
But. If my hands start to hurt while typing, I'm definitely trying something like that as my first keyboard experiment.