This would probably push some high-end audio professionals away from Logic. One of the niches Mac Pro has been popular is audio production. And with cheesegrader the ability to slot in many-many different audio interfaces into a box instead of dangling out to various PCIe enclosures has been a big win.
Here's a good video how it looks like: https://www.youtube.com/watch?v=kIQINCWMd6I&list=PLi2i2YhL6o... (at 1:40 Neil Parfitt shows Mac audio setup his before and after).
The video you linked is from 2019. A lot has changed with Thunderbolt capability and the Studios now have enough ports/bandwidth to handle audio processing needs to multiple boxes.
Feels like it'd just create a market for a big rack-mountable multi-bay PCIe enclosure, with its own internal power supply, that you could connect with one ore more thunderbolt cable. I don't see any reason why a solution built around a Mac Studio should have to be significantly more cluttered.
I don't know if such a solution exists right now, but I'm thinking there's a fair chance it will soon as the Mac Pro disappearing creates a demand for something like it.