Popular apps? Probably not many.

But in the field of integrated circuit design there’s lots of apps that are Linux-only. I’ve tried to run some of them in containers on Mac. But XQuartz is awful.

If they ever transitioned to Wayland perhaps this would let us run these apps on Mac in a nice way.

On the other hand some of them have started getting ARM builds (for running simulations on certain cloud environments) so maybe native Mac GUI builds could happen someday soon.