Would love to see a study looking at people who spend significant time in video games that require spatial navigation.
That could even be a form of therapy after diagnosis (which seems to become easier with biomarkers).
Look at https://seaheroquest.com/papers this is a game I designed and developed that links spatial performance to population scale navigation changes across 4.3m people.
Vsauce did a video about how League of Legends can affect spatial navigation and the brain: https://www.youtube.com/watch?v=1RHsAUyFCAM It seemed a bit odd to me since LoL isn't especially navigation-heavy, but Michael from Vsauce later confirmed he was actually playing LoL (they just weren't allowed to name it or show it directly - https://www.reddit.com/r/vsauce/comments/7igkve/what_game_do...).