The premise for this research question is related in part to work from Dr. Eleanor Maguire (who I just learned died last year at only 55) and her team on hippocampal anatomy and careers involving spatial navigation, including taxi drivers. A connection that may be of interest to HN readers: Demis Hassabis was one of Maguire's doctoral students, although he does not appear to have worked on the project most relevant to this study.