>The engineers at NASA believe it is safe.

it doesn't matter.

https://en.wikipedia.org/wiki/Artemis_II

"It will be the second flight of the Space Launch System (SLS), the first crewed mission of the Orion spacecraft, and the first crewed mission beyond low Earth orbit since Apollo 17 in 1972."

such "second/first" were ok 60 years ago. Today the only reason for that is that the SLS isn't reusable while the cost is hyper-astronomical.

Today's tech complexity, engineering culture and overall managerial processes don't allow the first/second to succeed as a rule. Even the best - Space X - has got several failed launches back then for Falcon and now for Starship.

Of course we wish success, and it will probably succeed - just like the Russian roulette so aptly mentioned in the sibling comment.