I would not worry about running a distro. Most things are similar, there are some minor differences between the GNU applications and the FreeBSD alternatives. But for most people there is nothing to worry about. Most applications runs fine on BSD. Bind, PowerDNS, Java Applications, PostgreSQL, Python, rsync and many more. Getting PyTorch to work with Nvidia and Cuda is most likely another story.

My main culprit with FreeBSD is that upgrading the kernel is not a simple dnf update command. But its still easier than upgrading RHEL from 9 to 10.