There are significant, real differences in betting on a random number generator once a week and betting constantly on the real outcomes of individual behaviors. Most notably with sports, institutionalized prop bets destroy the integrity of the game.
At least with win/loss, the ability to outright manipulate the outcome for financial gain by players, coaches and refs is a lot harder to accomplish without detection. Prop bets? Who knows if a player or ref or coach made a decision on who gets the first 3pt basket of the second half?
Yeah I've never made a prop bet, or even a points bet, that feels too degenerate to me. I have occasionally made a $10 money line bet on a game and that does make it more interesting to me in that now I have a small stake in the outcome. YMMV.
And people do spend stupid amounts of money on Powerball tickets too. I just think if the state is running a numbers racket, that they don't have much of a leg to stand on when they want to regulate other gambling.