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A_D_E_P_Tyesterday at 11:02 AM2 repliesview on HN

Sweeping statements in biochemistry must be made with caution. It is well known that there are some small peptides that are absorbed following oral administration.

...BPC-157 itself is said to be among this class. As are certain milk tripeptides: https://en.wikipedia.org/wiki/Lactotripeptides

Interestingly enough, those two, as well as Gly-Pro-Hyp, are proline/hydroxyproline-rich, which might suggest that proline-rich small peptides are resistant to degradation in the gut.

Anyway, in general oral proteins and peptides are broken down prior to systemic absorption, but not always...


Replies

oa335yesterday at 12:36 PM

> It is well known that there are some small peptides that are absorbed following oral administration. ...BPC-157 itself is said to be among this class

Do you know of any studies that suggest BPC-157 absorption from gut?

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staticassertionyesterday at 11:21 AM

I'm in agreement. It's the article that made the sweeping statement.