It was really the 386 that was the beginning of modern computing, since it had a mmu.
Several operating systems on 286 (eg Xenix, Coherent, OS/2) used its MMU for multitasking and memory protection. See https://en.wikipedia.org/wiki/Intel_80286#Protected_mode
Except the 486 had hardware floating point, essential for technical work.
Several operating systems on 286 (eg Xenix, Coherent, OS/2) used its MMU for multitasking and memory protection. See https://en.wikipedia.org/wiki/Intel_80286#Protected_mode