Another case based on interstate commerce: the US ban on racial segregation. The example given, iirc, was restaurant competition across state lines.
I wouldn't be surprised if this one unironically goes given that Uber/Lyft are fully doing "women only" ride shares now.
Gen Z / Alpha have embraced X-"realism" and fully accept essentialism/reject "intersectionality". They're far more conservative/prudish than millennials, even at their young age.
The interstate commerce clause is just craziness. It touches everything and gives justification to regulate nearly anything.