I've used ` as prefix for years now. Considering how often you switch windows/panes, I reckon using a single character has saved me hours per year. :D

It rarely conflicts with whatever I'm doing, but I have a binding to temporarily switch it to `C-a` and back, which I almost never use.

Oh, and I've used this themepack[1] for years as well.

Actually, here's my config[2] if someone finds it useful. I can't claim ownership of it, and probably stole it from somewhere I don't remember anymore.

BTW, the author's site https://rootloops.sh/ is certainly... something. :)

[1]: https://github.com/jimeh/tmux-themepack

[2]: https://gist.github.com/imiric/9bd3e5b7fc5e1468d05abc674f42e...