Interesting, I have used Fastmail for probably a decade plus at this point, and whether it's my obsessive rating of false negatives and positives, it is amazingly rare that I get spam slip into my inbox (maybe one message a week from ~100/day received, while my spam folder gets about 10/day).
I, too, mark all positives and negatives obsessively, but still get the same obvious spam in my inbox too often for my liking. Still, though, I love Fastmail.