Receive email, render page with the email and a reply section and a unique ID, print it out physically
Human picks up all the sheets out of the printer, writes out replies with pen
Human puts the stack of answered email sheets in a multi-page scanner
Scanner physically scans them, agent transcribes them and matches them back to the incoming emails via the unique ID on each sheet, sends replies
You could adjust this flow for anything where human input is just one part of a larger sequence: just add print -> write -> scan into your flow where you'd normally have a human type. It's kind of a rebirth of faxing
I will say scanners are somewhat unergonomic, but if you had a high enough definition camera, you could photograph the document in its "natural environment". Granted, it's harder to get an evenly lit picture that way, but I think it's a nicer interface.
I always wished I could throw my Pocketmod[0] in the scanner at the end of the day and have a nice new one with any notes I wanted to carry over to the next day freshly printed and waiting in the morning.
On one of my first qualified jobs, my manager (a lovely older lady) did exactly this. All incoming emails were printed and put into a binder. Then she would go home, write an answer with a pen on the back side of every single one, and on the next day write a new email to the recipient. 10-15 % of all emails she sent this way would bounce because she had written the address incorrectly.
When I showed her the reply button in Eudora (this was in 2001), she was so happy that she bought me a cake.
She struggled with IT but was tack sharp otherwise. So far she's the only boss I've ever really liked.