Looking only at connections to Tokyo is a bit reductionist (difficult to believe, but yes, there are cities outside of Tokyo that people go to!). As a mere matter of geography, there are unavoidably fewer trains to Tokyo (it's on the opposite side of the island). Using that same methodology, it would be good to see how many trains from Hamamatsu have a direct connection to the biggest metropolis near Tokuyama: Fukuoka. That way we can measure which city is the best for getting to the opposite side.

The total number of trains with a direct connection from Hamamatsu to Fukuoka is, at least based on all the info I can find, zero.

Or even a much closer city that people in Hamamatsu would frequently go to: Hiroshima. Also zero direct connections without a transfer.

People in Tokuyama can go direct to Fukuoka and Tokyo. They can do a transfer at Osaka in the case of non-direct trains. They're very much better set up than Hamamatsu.