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butvacuumlast Sunday at 7:37 AM3 repliesview on HN

buried the lede, imho: we have enough DNA profiles to match their sampling up with.

I'm always stunned when reminded that a full genome sequencing has gone from Human Genome Project's extreme cost and (edit: glacial) speed to using seqencing as the easy button.

I hear we've also got machines that'll seqence, fit on a bench, and cost high five/low six figures. They've got issues to work out still though- iirc something about damaged sections causing issues.


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cmrx64last Sunday at 8:19 AM

four figures these days. fits in your hand. nanopore is a revolution. https://nanoporetech.com/products/sequence/minion

there’s youtubers that have videos about doing this in a home wetlab. very achievable. some amateur soil biologists using this to try and sample microdiversity as the planet… humanifies.

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smoldertoday at 8:16 AM

Paleontology has been really helped by the ease of sequencing, to the point where many evolutionary arguments are moot. Humans are apes, birds are dinosaurs. Some people still dispute it, but not with evidence on their side.

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globular-toasttoday at 8:17 AM

Should be noted, though, the cheaper/quicker techniques do still come with compromises compared to the "gold standard" technique used for the Human Genome Project.