It remains to be seen how well F-35s actually perform in that role against an adversary with modern anti-air defense and with modern drone-based tactics.
Both Russia and Ukraine learned to avoid concentrating forces, so what are you going to strike? Use an F-35 to attack a single Jeep with a mounted machine gun? F-35 has limited range and carries very limited armament, so you can't just carpet-bomb everything. At some point, you'll need to use much less survivable heavy bombers.
F-35s have done pretty well in both Israeli and US hands against the Russian supplied SAM systems.
And if these vaunted Russian IADs can't stop Ukrainian drones with a RCS the size of a barn, they stand little chance against a stealth fighter.
Strike the stuff that can't move: government offices, factories, bridges, dams, power plants, ports, logistics hubs. The heavy B-2 bombers are themselves quite survivable, and were in fact used in the initial strikes.
Oh I love shopping lists, let's see. The FSB HQ, SVR HQ, Rosgvardiya HQ; tens of Army offices across the city. Roscosmos HQ, listening stations for the satellite network. Precision mechanics, optics and electronic foundries manufacturing sites in Khimki, Lubertsy, Lytkarino, Krasnogorsk and Zelenograd. Kosmos concert hall on Militia Day. Am sure there's more good spots along Rublevskoye highway too.
And if there are still some GBUs left after all that, the Kremlin and even the bloody Mausoleum.