> We used to spray DDT everywhere. This isn't exactly a resounding recommendation. Perhaps there's a case for using as little additives in farming as is possible

It's not relevant to glyphosate, but there is such a thing. It's called Integrated Pest Management. I only know it wrt fruit crops. The main idea is to use the least-intrusive methods first, and pesticides last. For example, sanitation comes first: remove last year's debris where larvae and spores have over-wintered.

Glyphosate isn't a pesticide (unless it kills host plants? maybe?)