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Tade0today at 9:31 AM3 repliesview on HN

> Stay up late because I’m wired on caffeine and dopamine from scrolling.

I wish people didn't overuse certain terms. Dopamine has a half life of 2 minutes in the body. It can't possibly keep you up at night.

It's just the caffeine, which in turn has a half-life of several hours. Also below a certain level it's eliminated approximately exponentially, so there's a long tail of residual caffeine.


Replies

bashkiddietoday at 9:42 AM

> Dopamine has a half life of 2 minutes in the body.

May be true.

But doing "rewarding" work encourages your body to emit more dopamine. Some people call it "the flow", others "hyperfocus", but it is a constant stream of dopamine that keeps you doing what you currently do. And you can interfere with the emittance and absorbtion by using caffeine.

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MrOrelliOReillytoday at 9:37 AM

> It’s just the caffeine

Fair enough if the use of “dopamine” is imprecise, but excessive screen time / doomscrolling / shitposting is definitely enough to wire you awake on its own, without caffeine.

fragmedetoday at 9:45 AM

> Dopamine has a half life of 2 minutes in the body.

That's for IV dopamine, used in extreme circumstances. Natural dopamine lasts shorter than that!