The pen tool is the big thing --- the ability to move a point when placing it using the control key while drawing w/ the pen tool is one thing I really miss, and in the context of the UI, the overall clean and straight-forward organization and layout, as well as supporting standard forms, so alt frees an off-curve node from association w/ the matching other, while shift constrains.
I see, that is indeed a highly requested feature (along with a general overhaul of the Node tool to make alternative curve methods less janky).
I'm been playing with Freehand, and the one thing that really stands out to me is the Object dialog. Current vector editors have similar designs, but none are as powerful and straightforward at the same time as Freehand's. The swatch workflow is also pretty rigid, and gives you a good imagination of what the color separations/result would look like.