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dnauticsyesterday at 5:28 PM1 replyview on HN

how many therapeutic proteins are there that aren't mabs or ~naturally occurring proteins (insulin, modified insulins, hirudin, cerezyme etc)?

I can think of:

etanercept


Replies

toufkayesterday at 9:28 PM

A large and rapidly growing number.

The largest commercial classes of multi-domain therapeutic proteins include the crispr (and similar) that drive gene therapies, and the chimeric antigen receptors (and similar) that drive cell therapies.

But lead optimization there look different than this page’s efforts.

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