PyPy is not looking healthy right now - it's several versions behind in support and, while it's not dead, it looks like it might be settling down for a rest.

Obviously it's not easy to move the whole language of a big codebase, but I feel a lot of this stuff (fiddling with GC, JITing, type hints, and I'm dubious about the free-threading stuff) tries to take Python somewhere it isn't really good at, and if that's what you want, you really want a different language.