The elephant in the room is AI. The frontier LLMs seem to prefer Tailwind by default. And they do a good job with it--likely because coupling style definitions to your HTML document structure is the least overhead way for an LLM to write code. The alternative--reasoning about a platonic ideal CSS structure, mapping the document structure to that an inferring how the layout will look, then juggling all that while making iterative edits--is a lot more "cognitive" work!