alt Hacker NewsAnother very interesting possible benefit of ibogaine not mentioned in the article is potential for treating TBI.
from https://pubmed.ncbi.nlm.nih.gov/41883580/:
>Longitudinal analyses assessed cortical thickness, subcortical volume, and predicted brain age (pBA), estimated from T1 scans. pBA was significantly reduced at 1 month relative to baseline (-1.3 years). Cortical thickness analysis revealed post-treatment increases in 11 regions. Subcortical analyses revealed significant volumetric expansion in 8 regions. Magnesium-ibogaine therapy was associated with increased cortical thickness, subcortical expansion, and reduced pBA at 1 month.
Open-label study, no control group, and ibogaine was not the only compound administered.
Any study like this is nearly useless without a control group, unfortunately. There is no way to tell if the treatment caused the changes or if they naturally occurred over the study period.